Chinese Use: Sprain, injure acute or chronic pain, fracture, injury of teh tissues.
Modern studies on pharmacodynamic reveal that this product yields actions of analgesia, anti-inflammation and homeostasis
1.
Analgesia: For
experimental pain in mice, this product yields very remarkable analgesic
action, which, in the dose of 1g/kg of extract yields similar effect to
pethidine 75mg/kg. Oral administration of this product 1g/kg markedly decreases
the number of body torsion in mice induced by acetic acid, similar to the
action of pethidine 50mg/kg. Heat-plate method shows that this product 2.74g/kg
elevates the pain threshold in mice, similar to the action of pethidine
75mg/kg, only with shorter duration. The analgesic action of this product can
be totally blocked by naloxone, an antagonistic agent of opium receptor. Hence,
it can be said that this product yields an analgesic action similar to opiate.
2.
Anti-inflammation: Oral
administration of this product 1g/kg markedly inhibits the auricular
inflammatory swelling in mice caused by dimethyl benzene, also with similar
action on rat swollen feet caused by albumen. The effect reaches its peak 2~4
hrs after medication.
3.
Hemostasis: To mice,
1g/kg of this product is perfused to the stomach, with good coagulation action.
2.5 hrs after medication, it shortens the normal coagulation time.
Toxicological studies:
Gastric perfusion of this product to mice shows that the LD50 and
its confident-limit (90%) is 5.06±0.94g/kg.
Clinically, this product
was used in sprain , and acute and chronic pain in trauma, fracture and injury
of soft tissues.
633cases of all kinds of injury were treated with a total effective rate of 91%. It was especially good in some common ligament sprain, common injuries and soft tissue injuries. To chronic strain of the waist muscles, the analgesic action is satisfactory. It also ameliorates pain due to chest contusion or inner injury.
Excerpt
from A Guide to TCM Products, China Academy of Traditional Chinese
Medicine, 2003
This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any diseases.