Summary of
Modern Studies on Rukuaixiao (Mammary Care™)Capsule
Chinese Use: Hyperplasia of
mammary glands.
This product is indicated in hyperplasia of mammary
gland due to stagnated liver –qi, hemostasis and qi-stagnation. The treating
principles include soothing the liver, regulating qi, activating blood flow and
resolving stasis, dispersing mammary lumps.
In this recipe,
Folium Citri recticulatae is pungent, bitter with dispersing and descending
actions, pertains to the liver hannel, capable of soothing the liver,
regulating qi, dispersing stagnated accumulation and anti-swelling. It is used
as the monarchal ingredient. Radix Salviae miltiorrhizae is bitter-slightly
cold, capable of activating blood flowing, regulating menstruation, cooling
blood, resolving abscess, and is a main medicament for solving stasis. Semen
Vaccariae is bitter-plain, pertains to the liver channel, capable of activating
blood, promoting menstrual flow, promoting lactation, and resolving abscess.
Both are served as ministerial ingredients in the recipe. Fructus Meliae
toosandan is bitter-cold with discending action, pertains to the liver channel,
capable of clearing liver fire, reducing stagnant fever, activating qi to stop
pain., Spina Gleditsiae is pungeut-warm, with dredging action, capable of
dispersing swelling and expelling pus. Lumbricus is salty-cold, pertains to the
liver channel. All the above 3 ingredients are applied for strengthening the action
of activating blood, resolving stasis, regulating qi, dispersing mammary lumps,
and are served as the adjuvant and
servant ingredients. The recipe yields the actions of soothing liver-qi,
smoothing blood flow, dispersing mammary lump, as a result, the lumps and
stasis of liver-qi and blood are all resolved.
Modern studies on pharmacodynamics show that this product yields the actions of
improving blood flowing, anti-inflammation, regulating endocrine secretion.
1.
Improving blood
circulation: Radix Salvial miltiorrhizae, lumbricus, Fructus Meeiae toosandan
are capable of improving blood circulation.
2.
Anti-inflammation:
Radix Salvial miltiorrhizae, lumbricus, Folium Citri recticulatae all yield
actions of anti-inflammation, inhibiting inflammatory exudates and hyperplasia
of tissue fibres.
3.
Regulating hormone
secretion: Semen Vaccariae regulates hormone secretion, elevates the secretion
level of progesterone.
Toxicological studies: The greatest tolerant dosage of animal
oral administration is 217.2g/kg; an equivalent to 1061.06 times of an adult
oral dosage.
Clinically,
this product was applied in hyperplasia of mammary gland.
105 cases were treated with this product in a dose of
6 tablets, b.i.d., with 3 month as a therapeutic course. After 3 courses of treatment,
50 cases were cured; 16, ameliorated; 9, ineffective; 105 cases in the control
group (no treatment given), the cured rate was 86%.
Excerpt
from A Guide to TCM Products, China Academy of Traditional Chinese
Medicine, 2003
This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any diseases.