Summary of
Modern Studies on Duzhong Yutai (Healthy Pregnancy™) Capsule
Chinese Use: Habitual miscarriage, habitual abortion,threatened abortion.
Modern studies
on pharmacodynamics reveal that this product yields actions of promoting
secretion of ovarian hormone, promoting ovulation, and promoting the growth of
ovary and uterus.
1.
Promoting secretion of
ovarian hormone: Female rabbits are randomly assigned to experimental group and
control group. The former group is given 27.5g/kg of this product, once daily.
For the control group, no medication is given. Other treatments are the same as
the experimental group for 26 days. The animals are killed by air emboli on the
13th, 20th, 26th days after medication.
Internal sexual organs such as uterus and ovary are taken out for observation
of changes under naked eyes and microscope. It can be seen that: (1) Mild
hyperplasic of endometrium, with increased glands, marked secretion, which is
increased with the increase of medication days.(secretion is transition from
early to late stages ).For the control group , there are less glands ,with
proliferation: A few rabbits reveal secretion, but less conspicuous than the test
group. Thus, it can be inferred that this product may promote the secretion of
luteotrophic hormone, or promote the secretion function of female sex hormone.
(2) The ovary of rabbit in the medication group has more corpus lutcum. Those
rabbits receive medication over 21 days have luteum cells distributed over the
whole ovary. That in the control group, only in certain part of the ovary
without corpus hemorrhagicum. The formation and its existence are related to
the female sex hormone and pituitary luteotrophic hormone. Thus, it is inferred
that this product can promote the level of female sex hormone, or even excite
the hypothalamus-pituitary function.(3)The rabbits in medication group during
observation reveal overlapping sexual behavior, but absent in the control
group. This overlapping activity is an indication of oestrous period, based on
the stimulation of estrogen produced in the ovary, indicating that this product
stimulates the ovary to secret estrogen.
2.
Promotion of ovulation:
oral medication of this product is given (dosage 27.5g/kg) for over 21 days. In
some individual animals, corpus albicans and corpus hemorrhagicum can be seen
which is an indirect indication of ovulation.
3.
Promoting the formation
and growth of ovary and uterus: Female rabbit fed with this product (27.5g/kg)
for 26 days are examined for its ovary and uterus under the microscope. It can
be seen that the rabbits in medication group have richer blood supply to the
ovary and uterus than the control group. Since the ovarian blood supply does
affect its secretion, therefore, it can be concluded that this product can
promote blood circulation through which the metabolism of the ovary and uterus
is raised, and as a result their growth are promoted.
Clinically, this product was applied in habitual abortion and
threatened abortion.
1.
Prevention and
treatment of habitual and threatened abortion: Medication of this product (5g,
tid, with 3 months as a therapeutic course, for 1~3 courses, same below), 124
cases were treated, the total effective rate being 94.35%.
2.
Sterility: 10 male
cases were treated. Among them, 3 cases were impotence, 1 case of
non-ejaculation, 6 cases of abnormal seminal fluid. 7 female cases, among them,
2 cases of underdeveloped uterus, 5 cases were dysfunction of corpus luteum and
anovulation .1~3 courses of this product were given (3 months as a course), all
cases were cured and fertilized.
Excerpt from A Guide
to TCM Products, China Academy of Traditional Chinese Medicine, 2003
This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any diseases.